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2015 Research Conference Proceedings

The PML Consortium held a research conference on PML on August 25-26, 2015 at AstraZeneca Mölndal, Sweden. This conference brought together industry and academic researchers with epidemiologists and physicians to discuss clinical, immunological, and basic research topics relevant to JCV and PML. Proceedings of the conference were published in the Journal of NeuroVirology and can be downloaded below, with permission of Springer. Recordings of the majority of talks given at the conference are also available below.


2nd International Conference on Progressive Multifocal Leukoencephalopathy (PML) 2015: JCV virology, progressive multifocal leukoencephalopathy pathogenesis, diagnosis and risk stratification, and new approaches to prevention and treatment
Journal of NeuroVirology
December 2015, Volume 21, Issue 6, pp 702-705 (First online: 26 October 2015)
Andriani C. Patera , Scott L. Butler, Paola Cinque, David B. Clifford, Robert Elston, Robert L. Garcea, Eugene O. Major, Dejan Pavlovic, Ilse S. Peterson, Anne M. Ryan, Kenneth L. Tyler, Thomas Weber, on behalf of the PML Consortium
DOI 10.1007/s13365-015-0392-5

Recordings of Conference Presentations

Welcome and Introduction Day 1 on Vimeo.


Session 1: Virology

Virology Session: Axons, the Front Line Sensors on Vimeo.

Virology Session: Trafficking of BKPyV to the Nucleus on Vimeo.


Session 2: Pathogenesis

Pathogenesis Session: Blood brain barrier CNS immune surveillance on Vimeo.

Pathogenesis Session: Testing JC and BK PyV Antibody responses Why and How on Vimeo.

Pathogenesis Session: T-cell surveillance of the acute and persistently infected brain on Vimeo.


Day 1 Roundtable

Roundtable: Virology and Pathogenesis Sessions on Vimeo.


Session 3: Diagnosis and Risk Management

Diagnosis Risk Session: T-cell Immunityin PML and MS on Vimeo.

Diagnosis Risk Session: Biomarkers for JCV Infection on Vimeo.

Diagnosis Risk Session: PML Associated with Neurologic Therapies on Vimeo.

Diagnosis and Risk Session: PML Associated with autoimmune and autoinflammatory diseases on Vimeo.


Session 4: Clinical Trials & New Approaches to Prevention and Treatment

Clinical Trials and Treatments Session: PML treatment on Vimeo.

Clinical Trials and Treatments Session: Antisense therapy to JCV on Vimeo.

Clinical Trials and Treatments Session - Host Abelson-kinase inhibitors, JCV clearance and PML on Vimeo.

Clinical Trials and Treatments Session: Developing vaccines against JC Polyomavirus on Vimeo.


Day 2 Roundtable

Roundtable: Diagnosis and Risk and Clinical Trials and Treatments Sessions on Vimeo.