Featured Information    |     Sitemap    |    
Share | 

Identifying Symptoms

Symptoms of PML are diverse and may vary from patient to patient depending on what part of the brain is infected by the JC virus (JCV).1 They may include:2


As the disease progresses, symptoms become worse and severe disability or death often results.


If your doctor suspects that you may have PML, they may conduct an MRI (Magnetic Resonance Imaging) to detect any changes in your brain, and assess clinical symptoms (such as loss of language ability, personality changes, loss of coordination, and vision problems). To diagnose PML, they also need to conduct a test for JCV, which involves a spinal tap.


The PML Consortium encourages patients at higher risk of PML to be vigilant in working with their physicians to monitor for signs and symptoms of PML. If you are concerned about PML for any reason, please consult your physician for full background information and a monitoring plan.


Disclaimer: The information on this website is for informational purposes only and is not being provided for the purposes of medical advice. View site Terms of Use.


1 NINDS Progressive multifocal leukoencephalopathy Information Page. National Institute of Neurological Disorders and Stroke. http://www.ninds.nih.gov/disorders/pml/pml.htm. Updated September 27, 2011. Accessed September 2012.

2 Progressive multifocal Leukoencephalopathy. MedlinePlus. U.S. National Library of Medicine, National Institutes of Health. http://www.nlm.nih.gov/medlineplus/ency/article/000674.htm. Updated November 6, 2017. Accessed November 2017.